(Jan. 10th Issue) "To keep skin cells plump and your face radiant throughout a dehydrating winter, look for creams rich in hyaluronic acid, which draws moisture from the air and holds up to 1,000 times its weight in water."
• Hyaluronic acid, 100% concentration
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ABC's "The Miracle of Hyaluronic Acid"
with Connie Chung:
Below, world-famous make-up artist Nikki DeRoest (HelloToBeauty.com) reviews Ialuset from her home-base in Milan. Nikki's client-list includes guests on the famed Conan Obrien show, rockers Veruca Salt, The Real Housewives, Beverly Hills Magazine, Chiara Ferragni and even the legendary Dick Cavett.
20 Minutes, France Oct. 18 Issue
"For fighting wrinkles...IALUSET is the original skin repair cream. Rich in hyaluronic acid, it is considered by many women to be the best anti-wrinkle cream on the market."
"Hyaluronic acid is a hot skincare ingredient that hydrates and plumps dry and aging skin."
Red Online UK
"Hyaluronic acid, or sodium hyaluronate as it’s also known, has become a serious skincare staple. It’s the body’s own hydrating molecule, able to absorb up to 1000 times its own weight in water and responsible for keeping our skin plump, smooth and supple. Sadly, our natural levels deplete as we age, so fight off fine lines and a loss of skin tone."
About Hyaluronic Acid: Health and Anti-Aging Benefits and Historic Information
Hyaluronic Acid, also known as HA (or hyaluronan/hyaluronate), is a mucopolysaccharide, which is a type of naturally occurring carbohydrate found within the human body. The sugars that make HA a carbohydrate are several thousand long. When it is free and unbound to other molecules, hyaluronic acid binds to H20 making it thick like a gel. It is for this reason that hyaluron is one of the most heavily researched topics in healthcare now with hundreds of tests being conducted at present. Hyaluronic acid binds H20 thus lubricating joints, muscles, and skin. The gel-like properties and water-binding nature make HA very conducive to skin care and anti-wrinkle types of beauty products.
How was Hyaluronic Acid Discovered with Regard to Anti-Aging?
In a remote village outside of Tokyo there were studies done on the longevity and health of its senior residents which surprised the scientific community. Their diets were rich in hyaluronic acid which was offsetting typical ailments and aging found in other communities. Even for those who smoked into their nineties, their skin was less wrinkled and their physical and mental abilities were closer to those of people in their fifties and sixties. There is a special made for TV by ABC News with Connie Chung that goes into further detail about this village.
Hyaluronic Acid’s Effect on the Body and Overall Health
As the body ages, skin loses its elasticity and ability to replenish moisture both on the surface as well as within. Joints are cushioned by synovial fluid and cartilage, and as these wear out it explains why people need hip replacements, knee replacements, and so forth. When the skin, joints, and muscles have an abundance of hyaluronic acid, it slows down or could even be said to reverse aging like a fountain of youth. It sounds too good to be true, however, the studies have gathered enough data to provide proof.
Biochemistry of Hyaluronic Acid
HA is a Glycosaminoglycan, naturally produced by our bodies. In its natural state, hyaluronic acid is a large, high molecular-weight molecule made up of a repetitive sequence of two modified simple sugars. The first is glucuronic acid and the second is called N acetyl glucosamine. Because both compounds are negatively charged, when they are put together they repel producing an abnormally long stretched out molecule. HA molecules that are long and large in size produce a high viscosity (lubrication) effect which resists compression and allows our joints and skin to bear weight (source: Hyalogic).
First Uses of Hyaluronic Acid
In 1942, Endre Balazs first applied for a patent to use hyaluronic acid in synthetic egg whites. He then went on to become the worldwide expert on HA making the more discoveries concerning hyaluronic acid than any other scientist. This is of course long before the village outside of Tokyo was studied, however, it is clear that Balazs was not thinking of anti-aging initially.
Where is Hyaluron Found Inside Our Bodies?
Nearly every cell in the body contains hyaluronic acid, but it is more concentrated in some more than others. Depending on the body part, HA serves a different function. That said, hyaluronic acid is said to last only about one day before being broken down in our skin. For the rest of the body inside, it is said to last for approximately three days. This means of course that our bodies most constantly replenish our supply of HA. For more details about body parts that contain hyaluronic acid see the examples below:
Hyaluronic Acid for Plump, Youthful Lips
Probably the most plump, gel-like part of the body is the lips. When well hydrated, they look full and even glossy. They are comprised of connective tissue and collagen, and contain loads of hyaluronic acid. This is further evident when looking at the shiny lips of a well-fed baby in comparison to the thinner face and lips of aged populations.
Hyaluronic Acid and Healthy Gums
Connective tissue in the gums securing the teeth to the jaw contains large amounts of hyaluronic acid. Without enough HA the gums cannot function properly and support the necessary ligaments.
Hyaluronic Acid for Healthy Hair
Skin on the head is basically the same as skin elsewhere on the body, except it has roughly 100,000 hair follicles. This ‘bed’ of follicles depends greatly upon moisture and nutrients being delivered deep below the skin’s surface. Hyaluronic acid is a necessity in this process as well, again, due to the particles’ moisture-binding properties.
Beautiful Skin and Hyaluronan
Nearly half of all the body’s hyaluronic acid is found in the skin. Aside from the one or two small body parts mentioned above, the skin has the highest concentration of HA also. Both the deep epidermal layers and the outer layer which is visible to the naked eye contain hyaluronic acid. The younger the person, the more HA their skin contains giving it a more elastic appearance typically free of wrinkles. The hyaluronic acid molecule can support 1,000 times its own weight if water delivery.
Companies such as Ialuset of France have pioneered the use of hyaluronic acid in skin creams for the face. Serums also exist, however, they lack the same moisturizing benefits of creams while costing actually more. France is renowned for its high quality skin care research and products the world over. Some face creams aimed at fighting wrinkles have added small amounts of hyaluronic acid to their ingredients, however, concentrations are usually minimal to maximize profits. The best anti-wrinkle creams will say 100% hyaluronic acid on the packaging with minimal ingredients. The most sought-after HA cream on the market today is Ialuset hyaluronic acid from France with many celebrities and models that swear by it.
Hyaluronic Acid within the Skeletal System
As mentioned, Hyaluronic Acid is in all bones and their supporting cartilage. Each provide a self-regenerating support system for the body up to a certain point or age. Hyaline cartilage has the highest concentration of hyaluronic acid compared to all others. The name of this cartilage actually gets its name from hyaluronic acid. Hyaline cartilage is found at the ends of the long bones where bending happens providing cushioning for the skeleton. Hyaline cartilage is found in the human nose, ribs where it attaches to the sternum, and most of the larynx, trachea, and bronchial tubes in the lungs of many life forms including people.
Hyaluronic Acid in Synovial Fluid
Moveable joints like elbows and knees are comprised of bones and sacs of fluid that lubricate and cushion the bones. The balloon-like structure is filled with clear liquid called synovial fluid. Synovial fluid is a thick, or viscous, similar to clear vegetable oil. It acts like a pillow to absorb impacts as well as carry waste out of and nutrients into the joint.
Hyaluronic Acid in Ligaments and Tendons
If you imagine the human body as a set of skeletal bones and muscles that move it into action, there must be rubber-band like structures which hold it all together. Bones need holding together and muscles need attaching to bones and each other. All of this ‘connective tissue’ has hyaluronic acid in it. Another key ingredient is elastin and collagen. Most of these cells are non-living which is unique to much of the rest of the body. It is the hyaluronic acid which nourishes and acts as a buffer between the living and non-living parts.
Beauty is in the Eye of the Beholder (and Hyaluronic Acid)
The actual eye has a high concentration of hyaluronic acid. The vitreous humor is nearly all HA giving the eye its gel-like property. Nutrition is allowed into the eye while HA also acts to absorb impact providing protection. It has been documented that HA has been directly injected into the eye during surgeries to help retain the shape of the eyeball. Some studies claim that into our fifties, our eyes stop producing hyaluronic acid naturally, explaining certain eye problems with late onset.
APPROVED INDICATIONS: Ialuset has been clinically proven effective in the treatment of fibrinous and excluding wounds, potentially infected wounds, decubitis and leg ulcer and surgical wounds. *The use of Ialuset hyaluronic acid as an anti-wrinkle treatment is not an officially approved indication.
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